Paolo Cappella Selected Research

3-aminopyrazole

12/2007

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.

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Paolo Cappella Research Topics

Disease

10	Neoplasms (Cancer) 01/2017 - 04/2006
2	Colonic Neoplasms (Colon Cancer) 04/2012 - 02/2011
2	Carcinogenesis 05/2010 - 04/2010
1	Body Weight Changes 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Ovarian Epithelial Carcinoma 01/2017
1	Thalassemia 01/2015
1	Hemoglobinopathies 01/2015
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2015
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2012
1	Hematologic Neoplasms (Hematological Malignancy) 04/2012
1	Glioblastoma (Glioblastoma Multiforme) 02/2011
1	Aneuploidy (Aneuploid) 12/2010
1	Osteosarcoma (Osteogenic Sarcoma) 09/2006

Drug/Important Bio-Agent (IBA)

3	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2011
3	Phosphotransferases (Kinase)IBA 04/2012 - 12/2007
2	Pharmaceutical PreparationsIBA 01/2017 - 02/2012
2	Polo-Like Kinase 1IBA 04/2012 - 05/2010
2	danusertibIBA 02/2012 - 12/2007
2	Aurora KinasesIBA 04/2010 - 12/2007
1	CytokinesIBA 01/2021
1	PlatinumIBA 01/2017
1	MetalloporphyrinsIBA 01/2015
1	GlobinsIBA 01/2015
1	Cytarabine (Cytosar-U)FDA LinkGeneric 04/2012
1	Irinotecan (Camptosar)FDA LinkGeneric 04/2012
1	NMS P937IBA 04/2012
1	Proteins (Proteins, Gene)FDA Link 02/2012
1	Biological ProductsIBA 02/2012
1	CamptothecinIBA 02/2011
1	Temozolomide (Temodar)FDA LinkGeneric 02/2011
1	LuciferasesIBA 02/2011
1	benzyloxycarbonyl- aspartyl- glutamyl- valyl- aspartyl- aminoluciferinIBA 02/2011
1	D-luciferinIBA 02/2011
1	CaspasesIBA 02/2011
1	Caspase 3 (Caspase-3)IBA 02/2011
1	N- (2,6- diethylphenyl)- 1- methyl- 8- ((4- ((1- methylpiperidin- 4- yl)carbamoyl)- 2- (trifluoromethoxy)phenyl)amino)- 4,5- dihydro- 1H- pyrazolo(4,3- h)quinazoline- 3- carboxamideIBA 12/2010
1	EnzymesIBA 04/2010
1	3-aminopyrazoleIBA 12/2007
1	tyrosine receptor (receptor, tyrosine)IBA 12/2007
1	ThymidineIBA 09/2006
1	NocodazoleIBA 09/2006
1	Paclitaxel (Taxol)FDA LinkGeneric 09/2006
1	PHA 680632IBA 07/2006
1	Melphalan (Alkeran)FDA LinkGeneric 04/2006

Therapy/Procedure

4	Therapeutics 01/2021 - 12/2007
2	Oral Administration 04/2012 - 05/2010
1	Drug Therapy (Chemotherapy) 01/2017
1	Aftercare (After-Treatment) 02/2011